Integrin beta 7, Rabbit anti-Human,Mouse, Clone: FIB504, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP2810860.025MG

Catalog No. NB015717

Description

Integrin beta 7 Monoclonal specifically detects Integrin beta 7 in Human, Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Block/Neutralize.

Specifications

• Antigen: Integrin beta 7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: Flow Cytometry, Immunocytochemistry/Immunofluorescence, Block/Neutralize
• Gene Alias: Gut homing receptor beta subunit, integrin beta 7 subunit, integrin beta-7, integrin, beta 7
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: FIB504 recognizes an epitope on Integrin beta 7 subunit that overlaps completely with the epitope defined by Fib27 and Fib30, and also partially with the epitope defined by FIB21 and FIB22. In the mouse beta-7 is selectively found on the majority of mature lymphocytes, whereas a small subpopulation of thymocytes and bone marrow cells express beta-7. Beta-7 is also expressed in variable amounts in CD4 T memory cells. Integrin molecules mediate cell-cell and cell-extracellular matrix adhesion and are involved in lymphocyte homing, leukocyte recruitment to inflammatory sites, myogenesis, hemopoiesis, and melanoma metastasis.
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Isotype: IgG κ

• Applications: Flow Cytometry, Immunofluorescence, Blocking Assay
• Clone: FIB504
• Conjugate: Unconjugated
• Formulation: PBS
• Gene Symbols: ITGB7
• Immunogen: FIB504 was prepared by immunizing rats with TK1 cells.
• Quantity: 0.025 mg
• Research Discipline: Signal Transduction
• Gene ID (Entrez): 3695
• Target Species: Human, Mouse
• Form: Purified