ACROBiosystems Recombinant Protein;Human Integrin alpha 2b beta 3 (ITGAIIb&ITGB3) Heterodimer Protein;HEK293;1MG;IT3,Integrin alpha 2b beta 3,ITGAIIb&ITGB3,ITGAIIb&B3
Supplier: ACROBiosystems IT3H52W81MG
Recombinant Protein;Human Integrin alpha 2b beta 3 (ITGAIIb&ITGB3) Heterodimer Protein;1MG;Human ITGAIIb & ITGB3 (IT3-H52W8) is expressed from human 293 cells (HEK293). It contains AA Leu 32 - Arg 993 (ITGAIIb) & Gly 27 - Asp 718 (ITGB3) (Accession # P08514-1 (R887L) (ITGAIIb) & P05106-1 (ITGB3)).;Human ITGAIIb & ITGB3 Heterodimer Protein, produced by co-expression of ITGAIIb and ITGB3, has a calculated MW of 111.4 kDa (ITGAIIb) & 81.8 kDa (ITGB3). Subunit ITGAIIb is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB3 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 110-120 kDa, 125 kDa and 145 kDa due to glycosylation.;Immobilized Human Fibronectin at 5 μg/mL (100 μL/well) can bind Human ITGAIIb & ITGB3 (Cat. No. IT3-H52W8) with a linear range of 0.16-5 μg/mL (QC tested).;Immobilized Human ITGAIIb & ITGB3 (Cat. No. IT3-H52W8) at 1 μg/mL (100 μL/well) can bind Abciximab with a linear r
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