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IntegrinalphaL/CD11a Mouse anti-Mouse, Janelia Fluor 549, Clone: 87-6F9, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP142196JF549

Catalog No. NBP14296549

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

IntegrinalphaL/CD11aMonoclonalantibody specifically detects IntegrinalphaL/CD11a in Mouse samples.
Specifications

Specifications

IntegrinalphaL/CD11a
87-6F9
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Purified
ITGAL
The antibody reacts with the CD11a antigen.
Protein A or G purified
Adaptive Immunity, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Myeloid Cell Markers, Signal Transduction, Stem Cell Markers
Primary
3683
Mouse
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Janelia Fluor 549
50mM Sodium Borate with 0.05% Sodium Azide
CD11 antigen-like family member A, CD11a antigen, CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide, integrin alpha-L, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide), Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, lymphocyte function-associated antigen 1
Mouse
IgG1
0.1mL
Store at 4°C in the dark.
Monoclonal
CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin beta-2). A defect in beta-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections. Source: A BALB/c mouse was immunized and SP2/0 cells were used for fusion with splenocytes.
Documents
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