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  5. IOX 2, Tocris Bioscience™

IOX 2, Tocris Bioscience™

Catalog Number 445150
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
931398-72-0
C19H16N2O5
352.346
CAOSCCRYLYQBES-UHFFFAOYSA-N
iox2, iox 2, iox2 glycine, 2-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido acetic acid, 2-1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl amino acetic acid, 1-benzyl-4-hydroxy-2-oxoquinolin-3-yl formamido acetic acid, d0wa3e, iox-2, iox hplc, 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl glycine
54685215
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
This item is not returnable. View return policy
931398-72-0
C19H16N2O5
352.346
CAOSCCRYLYQBES-UHFFFAOYSA-N
iox2, iox 2, iox2 glycine, 2-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido acetic acid, 2-1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl amino acetic acid, 1-benzyl-4-hydroxy-2-oxoquinolin-3-yl formamido acetic acid, d0wa3e, iox-2, iox hplc, 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl glycine
54685215
2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O

Description

Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor

Potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) (IC50 = 21 nM). Displays over 100-fold selectivity for PHD2 over factor inhibiting HIF-1 (FIH-1) and histone demethylases JMJD2A, JMJD2C, JMJD2E and JMJD3. Cell permeable.
Formula Weight 352.34
Percent Purity >99%
Quantity 50 mg
Chemical Name or Material IOX 2

Safety and Handling

Recommended Storage Store at +4°C
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