Group I p21-activated kinase (PAK) inhibitor (IC50 = 2.5µM at PAK1). Targets the autoregulatory mechanism and promotes the inactive conformation of PAKs. Inhibits PAK1-mediated signaling in vivo; potential anti-tumor agent. Negative control PIR 3.5 (Cat. No. 4212) available.
Chemical Name: 1,1'-Dithiodi-2-naphthtol
CAS Number: 42521-82-4
Solubility: Soluble to 75mM in DMSO and to 10mM in ethanol with gentle warming
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