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  7. IQ 3, Tocris Bioscience™

IQ 3, Tocris Bioscience™

Catalog Number 455010
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
312538-03-7
C20H11N3O3
341.326
WBSWWONMTZEOGS-PTGBLXJZSA-N
iq 3, e-indeno 1,2-b quinoxalin-11-ylideneamino furan-2-carboxylate, 11h-indeno 1,2-b quinoxalin-11-one o-2-furanylcarbonyl oxime, 11z-indeno 1,2-b quinoxalin-11-ylideneamino furan-2-carboxylate
5405540
[(E)-indeno[1,2-b]quinoxalin-11-ylideneamino] furan-2-carboxylate
C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=NOC(=O)C5=CC=CO5
This item is not returnable. View return policy
312538-03-7
C20H11N3O3
341.326
WBSWWONMTZEOGS-PTGBLXJZSA-N
iq 3, e-indeno 1,2-b quinoxalin-11-ylideneamino furan-2-carboxylate, 11h-indeno 1,2-b quinoxalin-11-one o-2-furanylcarbonyl oxime, 11z-indeno 1,2-b quinoxalin-11-ylideneamino furan-2-carboxylate
5405540
[(E)-indeno[1,2-b]quinoxalin-11-ylideneamino] furan-2-carboxylate
C1=CC=C2C(=C1)C3=NC4=CC=CC=C4N=C3C2=NOC(=O)C5=CC=CO5

Description

Selective JNK3 inhibitor

Selective JNK3 inhibitor (Kd values are 66, 240 and 290 nM for JNK3, JNK1 and JNK2 respectively). Inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells (IC50 = 1.4 μM). Also inhibits TNF-α and IL-6 production in vitro.
Color Yellow
Quantity 10 mg
Formula Weight 341.32
Percent Purity >98%
Physical Form Solid
Chemical Name or Material IQ 3

Safety and Handling

Recommended Storage Store at +4°C
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