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IQGAP1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 221671AP

Catalog No. 50-173-3754


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Description

Description

DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.
Specifications

Specifications

IQGAP1
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P46940, Q9JKF1
HUMORFA01, IQGAP1, KIAA0051, p195, SAR1
Rabbit
IgG
150 μL
-20°C
Primary
29875, 8826
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
IQGAP1
Liquid
IQGAP1
IQGAP1 Fusion Protein Ag17821
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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