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IRF1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550512

Catalog No. PA550512


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Description

Description

The antibody detects endogenous levels of total IRF1 protein.

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppression. Diseases associated with IRF1 include gastric cancer, somatic and lung cancer.
Specifications

Specifications

IRF1
Polyclonal
Unconjugated
IRF1
Liquid
IRF1
Synthetic peptide corresponding to a region derived from internal residues of human interferon regulatory factor 1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1.5 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P10914, P15314
IRF-1, MAR
Rabbit
IgG
100 μL
-20°C
Primary
16362, 3659
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