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ITCH Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 209201AP

Catalog No. 50-173-3156


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Description

Description

Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT domain. It can act as a transcriptional corepressor of p45/NFE2 and may participate in the regulation of immune responses by modifying Notch-mediated signaling. It is highly similar to the mouse Itch protein, which has been implicated in the regulation and differentiation of erythroid and lymphoid cells.
Specifications

Specifications

ITCH
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8C863, Q96J02
AIF4, AIP4, ITCH, NAPP1, NFE2 associated polypeptide 1
Rabbit
IgG
150 μL
-20°C
Primary
16396, 83737
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
ITCH
Liquid
ITCH
ITCH Fusion Protein Ag15120
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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