ITGB4 Mouse anti-Human, Clone: 10B10D5, Abnova™
Mouse monoclonal antibody raised against partial recombinant human ITGB4.
Manufacturer: Abnova Corporation MAB12480
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
|Mouse monoclonal antibody raised against partial recombinant human ITGB4.|
|In ascites (0.03% sodium azide)|
|ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to amino acids 1619-1822 of human ITGB4.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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