PDGFRB Mouse anti-Human, PE, Clone: 18A2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen A15786
DescriptionPDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, alpha and beta coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, alpha and beta.
|CD140B-transfected NIH-3T3 cells|
|PBS with 0.2% BSA and 15mM sodium azide|
|PDGF Receptor beta, JTK12, PDGFR, PDGFR1, CD140 antigen-like family member B, PDGF-R-beta, beta-type platelet-derived growth factor receptor|
|4° C, store in dark, DO NOT FREEZE!|
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