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ITIH4 Mouse anti-Human, Clone: CL1858, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524630

Catalog No. PIMA524630


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Description

Description

Immunogen sequence: LAYSFVTPLT SMVVTKPDDQ EQSQVAEKPM EGESRNRNVH SAGAAGSRMN FRPGVLSSRQ LGLPGPPDVP DHAAYHPFRR LAILPASAPP ATSNPDPAVS RVMNMKIEET TMTTQTPA Highest antigen sequence identity to the following orthologs: Mouse - 35%, Rat - 36%. Binds to an epitope located within the peptide sequence LSSRQLGLPGPPDVP as determined by overlapping synthetic peptides.

the inter-alpha-trypsin inhibitor (ITI, I-alpha-I) family, a typical and classical example for protein-glycosaminoglycoprotein (PGP) complexes, occurs constitutively in plasma at relatively high concentrations and is a result of alternate combinations of three kinds of heavy chains with a common light chain, the bikunin proteoglycan. Bikunin has two proteinase inhibotor domains and belongs to the Kunitz-type protease inhibitor family; it displays an inhibitory activity against trypsin, leukocyte elastase and plasmin. The heavy chains do not have any protease inhibitory properties but have the capacity to interact in vitro and in vivo with hyaluronic acid and this binding promotes the stability of the extra-cellular matrix. The ITI protein family is suspected of playing a key role in the extra-cellular matrix biology.
Specifications

Specifications

ITIH4
Monoclonal
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q14624
DKFZp686G21125, H4P, IHRP, ITIHL1, PK120
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3700
Immunohistochemistry, Western Blot
CL1858
Unconjugated
ITIH4
Liquid
ITIH4
Recombit protein corresponding to Human ITIH4
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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