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Alfa Aesar™ Itraconazole, 98%

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Quantity:
1g
5g
25g
84625-61-6
C35H38Cl2N8O4
710.672
MFCD00870168
VHVPQPYKVGDNFY-VXTATNQMSA-N
Oriconazole; R51211
45039617
4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(3,3,4,4,4-pentadeuteriobutan-2-yl)-1,2,4-triazol-3-one
CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
84625-61-6
C35H38Cl2N8O4
710.672
MFCD00870168
VHVPQPYKVGDNFY-VXTATNQMSA-N
Oriconazole; R51211
45039617
4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-(3,3,4,4,4-pentadeuteriobutan-2-yl)-1,2,4-triazol-3-one
CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl
Applications
Itraconazole is a triazole antifungal agent. It is used to inhibit cytochrome P-450-dependent enzymes and ergosterol synthesis. It has been used against histoplasmosis, blastomycosis, cryptococcal meningitis, and aspergillosis. It′s different formulations are used to study Candida strains in murine invasive infections. It has been used to study proliferative changes of the forestomach mucosa in alloxan-induced diabetic rats..

Solubility
Insoluble in water. Solube in chloroform at 50 mg/ml. Slightly soluble in ethanol or methanol

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Merck Index 14,5245
Solubility Information Insoluble in water; Solube in chloroform at 50mg/mL; Slightly soluble in ethanol or methanol
Formula Weight 705.63
Physical Form Powder
Percent Purity 98%
Color White
Melting Point 166°C
Quantity 1g
Chemical Name or Material Itraconazole

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : XZ5481000

storageNote1 : 2° to 8°C