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UbpbioSupplier Diversity Partner IXAZOMIB (MLN-2238), 25MG DFS Item

Manufacturer:  UbpbioSupplier Diversity Partner F1111

Inhibitors – Ixazomib (UBPBio catalog# F1110, F1111) – Ixazomib (MLN2238) (commercial name: Ninlaro®) is the first and only FDA-approved oral proteasome inhibitor for the treatment of multiple myeloma. It reversibly inhibits the chymotrypsin-like activity of proteasomes with IC50 of 3.4 nM in cell-free assays, also inhibits the caspase-like and trypsin-like activities of proteasome with IC50 of 31 and 3500 nM, respectively.

Catalog No. 50-112-6893


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