Ubpbio IXAZOMIB (MLN-2238), 5MG
Manufacturer: Ubpbio F1110
Inhibitors – Ixazomib (UBPBio catalog# F1110, F1111) – Ixazomib (MLN2238) (commercial name: Ninlaro®) is the first and only FDA-approved oral proteasome inhibitor for the treatment of multiple myeloma. It reversibly inhibits the chymotrypsin-like activity of proteasomes with IC50 of 3.4 nM in cell-free assays, also inhibits the caspase-like and trypsin-like activities of proteasome with IC50 of 31 and 3500 nM, respectively.
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