J Chain Mouse anti-Human, Clone: OTI2B1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525839
DescriptionJ chain is a small glycopeptide with MW of 15kDa. It is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsils and lymph nodes. B cells discrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|IGCJ, JCH, IgJ chain, immunoglobulin J chain|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of IGJ produced in HEK293T cell|
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