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JAML Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 213021AP

Catalog No. 50-173-3358


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Description

Description

AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.
Specifications

Specifications

JAML
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q86YT9
AMICA, AMICA1, CREA7 1, CREA7 4, Gm638, JAML
Rabbit
IgG
150 μL
-20°C
Primary
120425
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
JAML
Liquid
JAML
JAML Fusion Protein Ag15900
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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