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Tocris™ K 858

Selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor

Manufacturer:  Tocris™ 3703/50

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Catalog No. 37-035-0R

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For Research Use Only



Selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor (IC50 = 1.3µM). Induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells. Displays no effect on microtubule dynamics. Preferentially induces mitotic arrest in cancer cells.
  • Chemical Name: N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadiazol-2-yl)acetamide
  • Formula: C13H15N3O2S
  • CAS Number: 72926-24-0
  • Solubility: Soluble to 100mM in DMSO and to 10mM in ethanol
  • Purity: >99
Description & Specifications


K 858
K 858
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