Thermo Scientific Chemicals Kanamycin, 50 mg/mL in Distilled Water, Sterile-filtered PROMO

Description

Kanamycin monosulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity.

General Description

• Kanamycin monosulfate is the sulfate salt form of kanamycin A
• It was isolated from Streptomyces kanamyceticus
• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
• This compound is also involved in translating prokaryotic ribosomes
• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Specifications

Chemical Identifiers

• CAS: 25389-94-0
• Molecular Formula: C18H38N4O15S
• Molecular Weight (g/mol): 582.575 g/mol
• MDL Number: MFCD00070289
• InChI Key: OOYGSFOGFJDDHP-IZQIRFRQSA-N
• PubChem CID: 134129479
• IUPAC Name: (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
• SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

• Type: Kanamycin
• Physical Form: Liquid
• Quantity: 50 mL
• Solubility Information: Fully miscible in Water. Insoluble in acetone,chloroform,ether,ethyl acetate,and Alcohol.
• Chemical Name or Material: Kanamycin, 50 mg/mL in Distilled Water, Sterile-filtered

Safety and Handling

Hazard Category	H317-H334-H360FD
Hazard Statement	GHS H Statement: H334-H360-H317. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May damage fertility or the unborn child. May cause an allergic skin reaction.
Precautionary Statement	P201-P202-P261-P272-P280g-P281-P285-P302+P352-P304+P341-P308+P313-P333+P313-P342+P311-P363-P501c
TSCA	No
storageNote1	-30°C to -10°C
Recommended Storage	Store at -20°C

RUO – Research Use Only