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Kappa Light Chain Mouse anti-Human, Alexa Fluor™ 594, Clone: HP6053, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234639AF594

Catalog No. NP234639A94


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Description

Description

Kappa Light Chain Monoclonal antibody specifically detects Kappa Light Chain in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

Kappa Light Chain
HP6053
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Conjugated, Purified
IGKC
Purified human Ig kappa chain
Protein A purified
Adaptive Immunity, Immunology
Primary
3514.0
Human
ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 594
50 mM sodium borate with 0.05% sodium azide
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin′s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
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