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Kappa Light Chain Antibody (TB28-2), Alexa Fluor™ 750, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP234721AF750
Description
Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
Kappa Light Chain | |
Monoclonal | |
Alexa Fluor 750 | |
50 mM sodium borate with 0.05% sodium azide | |
IGKC | |
Human IgG-kappa myeloma protein | |
0.1 mL | |
3514 | |
Human | |
IgG1 κ |
Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) | |
TB28-2 | |
Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen | |
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809 | |
Mouse | |
Protein A or G purified | |
Primary | |
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. | |
Store at 4°C in the dark. |
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