Kappa Light Chain Mouse anti-Human, Clone: TB28-2, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2342560.2MG
DescriptionKappa Light Chain Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunohistochemistry (Frozen).
|Kappa Light Chain|
|Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 0.5-1ug/ml|
|HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809|
|Protein A purified|
|Store at 4C.|
|This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)|
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|Human IgG-kappa myeloma protein|
|Adaptive Immunity, Immunology|
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