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KB SRC 4, Tocris Bioscience™

Catalog No. p-4816566
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent and selective c-Src inhibitor

Potent and selective c-Src inhibitor (Ki = 44 nM); does not inhibit c-Abl at concentrations up to 125 μM. Selective between Src family members (Kd values are 86, 160, 240, 720, 3200, 4400, and >40,000 nM for c-Src, Lck, Fgr, Yes, Lyn, Hck and Fyn respectively). Significantly inhibits cell growth in 4T1 mammary carcinoma tumor cells.

Chemical Identifiers

CAS 1380088-03-8
Molecular Formula C32H23ClN8
Molecular Weight (g/mol) 555.042
InChI Key UHIZYQVRKSWIFO-UHFFFAOYSA-N
Synonym kb src 4, 1-3-1-1,1'-biphenyl-3-ylmethyl-1h-1,2,3-triazol-5-yl phenyl-3-4-chlorophenyl-1h-pyrazolo 3,4-d pyrimidin-4-amine, 1-3-1-1,1-biphenyl-3-ylmethyl-1h-1,2,3-triazol-5-yl phenyl-3-4-chlorophenyl-1h-pyrazolo 3,4-d pyrimidin-4-amine
PubChem CID 73349077
IUPAC Name 3-(4-chlorophenyl)-1-[3-[3-[(3-phenylphenyl)methyl]triazol-4-yl]phenyl]pyrazolo[3,4-d]pyrimidin-4-amine
SMILES C1=CC=C(C=C1)C2=CC(=CC=C2)CN3C(=CN=N3)C4=CC(=CC=C4)N5C6=C(C(=N5)C7=CC=C(C=C7)Cl)C(=NC=N6)N

Specifications

Quantity 10 mg
Formula Weight 555.03
Percent Purity >98%
Chemical Name or Material KB SRC 4

Safety and Handling

Recommended Storage Store at +4°C
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