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  8. KC 12291 hydrochloride, Tocris Bioscience™

KC 12291 hydrochloride, Tocris Bioscience™

Catalog Number p-4784067
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
181936-98-1
C22H28ClN3O3S
449.994
KIJPRQYBNQKUAU-UHFFFAOYSA-N
kc 12291 hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanamine hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanaminehydrochloride, n-3,4-dimethoxyphenethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine hydrochloride, 2-3,4-dimethoxyphenyl ethyl methyl 3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl amine hydrochloride, n-2-3,4-dimethoxyphenyl ethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine-hydrogen chloride 1/1
22902387
N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propan-1-amine;hydrochloride
CN(CCCOC1=NSC(=N1)C2=CC=CC=C2)CCC3=CC(=C(C=C3)OC)OC.Cl
This item is not returnable. View return policy
181936-98-1
C22H28ClN3O3S
449.994
KIJPRQYBNQKUAU-UHFFFAOYSA-N
kc 12291 hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanamine hydrochloride, 3,4-dimethoxy-n-methyl-n-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl benzeneethanaminehydrochloride, n-3,4-dimethoxyphenethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine hydrochloride, 2-3,4-dimethoxyphenyl ethyl methyl 3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propyl amine hydrochloride, n-2-3,4-dimethoxyphenyl ethyl-n-methyl-3-5-phenyl-1,2,4-thiadiazol-3-yl oxy propan-1-amine-hydrogen chloride 1/1
22902387
N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propan-1-amine;hydrochloride
CN(CCCOC1=NSC(=N1)C2=CC=CC=C2)CCC3=CC(=C(C=C3)OC)OC.Cl

Description

Orally active atypical Na+ channel blocker; cardioprotective

Orally active atypical voltage-gated sodium channel blocker. Inhibits sustained sodium currents (INaL) and prevents diastolic contracture in isolated atria in vitro (IC50 values are 9.6 and 0.55 - 0.79 μM respectively). Displays anti-ischemic, bradycardic and cardioprotective activity in vivo.
Quantity 10 mg
Formula Weight 449.99
Percent Purity >97%
Chemical Name or Material KC 12291 hydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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