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KCNIP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 201921AP

Catalog No. 50-173-2760


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Description

Description

This antibody can recognize the 31 kDa and 29 kDa isoforms.

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.
Specifications

Specifications

KCNIP2
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9JJ69, Q9NS61
KCHIP2, KCNIP2
Rabbit
IgG
150 μL
-20°C
Primary
30819, 80906
Western Blot
Unconjugated
KCNIP2
Liquid
KCNIP2
KCNIP2 Fusion Protein Ag14111
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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