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Kir2.2 (KCNJ12) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548887

Catalog No. PA548887

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Specifications

Specifications

Kir2.2 (KCNJ12)
Polyclonal
PBS with 0.09% sodium azide
Q14500
ATP-sensitive inward rectifier potassium channel 12, Inward rectifier K(+) channel Kir22, IRK-2, Inward rectifier K(+) channel Kir22v, Potassium channel, inwardly rectifying subfamily J member 12, KCNJ12, IRK2, KCNJN1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3768
Western Blot
Unconjugated
KCNJ12
Liquid
KCNJ12
KLH conjugated synthetic peptide between 405-433 amino acids from the C-terminal region of human KCNJ12.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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