KCNMB2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587770

Catalog No. PIPA587770

Description

Immunogen sequence: TLLRSYMQSV WTEESQCTLL NASITETFNC SFSCGPDCWK LSQYPCLQVY VNLTSSGEKL LLYHTEETIK INQKCSYIPK CGKNFEESMS LVNVVMENFR KYQHFSCYSD PEGNQKSVIL TKLYSSN; Positive Samples: Mouse kidney, Mouse brain, Mouse lung, Rat brain, Rat kidney; Cellular Location: Membrane, Multi-pass membrane protein

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.

Specifications

• Antigen: KCNMB2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNMB2
• Gene Symbols: Kcnmb2
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Concentration: 2.4 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q811Q0, Q9CZM9, Q9Y691
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10242, 294961, 72413
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid