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KCNQ3 Rabbit anti-Human, Porcine, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 199661AP

Catalog No. 50-173-2629


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Description

Description

The antibody recognizes the C-term of KCNQ3.

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1-5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.
Specifications

Specifications

KCNQ3
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43525
BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3
Rabbit
IgG
150 μL
-20°C
Primary
100157152, 3786
Western Blot
Unconjugated
KCNQ3
Liquid
KCNQ3
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Porcine
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