Invitrogen™ KCNT1 Monoclonal Antibody (N3/26)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527609

Catalog No. PIMA527609

Description

1 μg/mL of MA5-27609 was sufficient for detection of Slo2.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 140kDa. Weak human detection.approximately Does not cross-react with KCNT2/Slo2.1/Slick.

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: KCNT1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q5JUK3, Q6ZPR4, Q9Z258
• Gene Symbols: Kcnt1
• Immunogen: Fusion protein amino acids 1168-1237 of rat Slo2.2 (Slack).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Microarray
• Clone: N3/26
• Conjugate: Unconjugated
• Gene: Kcnt1
• Gene Alias: bA100C15.2; C030030G16Rik; EIEE14; ENFL5; KCa4.1; KCa4.1KIAA1422FLJ41282; Kcnt1; KIAA1422; Potassium channel subfamily T member 1; potassium channel subunit (Slack); potassium channel, sodium activated subfamily T, member 1; potassium channel, sodium-activated subfamily T, member 1; potassium channel, subfamily T, member 1; potassium sodium-activated channel subfamily T member 1; rSlo2; Sequence like a calcium-activated K+ channel; sequence like a calcium-activated potassium channel subunit; Slack; slo2; Slo2.2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 227632, 57582, 60444
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov