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KDEL Rabbit anti-Human, Unconjugated, Clone: JB42-04, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA534715

Catalog No. PIMA534715


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Description

Description

Positive Control: Rat testis tissue, Mouse testis tissue, 293, HepG2, A549, 293T, rat epididymis tissue, human placenta tissue, human stomach cancer tissue, mouse small intestine tissue.

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
Specifications

Specifications

KDEL
JB42-04
Unconjugated
HSPA5
Liquid
Hsp90b1, HSPA5, Kdelr1
Recombinant protein
Protein A
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
P11021, P14625, P24390
78 kDa glucose-regulated protein; 8030486F04Rik; 94 kDa glucose-regulated protein; AL022860; AU019543; AW215843; baffled; Binding-immunoglobulin protein; BiP; D2Wsu141e; D2Wsu17e; ECGP; Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum resident protein 99; Endoplasmin; ER lumen protein-retaining receptor 1; ERD2; ERD2.1; ERp99; GP96; gp96 homolog; GRP78; GRP-78; Grp94; GRP-94; HDEL; Heat shock protein 70 family protein 5; Heat shock protein 90 kDa beta member 1; Heat shock protein family A member 5; HEL35; HEL-S-125m; HEL-S-89n; Hsce70; HSP70 family protein 5; HSP90B1; HSPA5; I79_019946; I79_020931; Immunoglobulin heavy chain-binding protein; KDEL; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDELR1; Lys-Asp-Glu-Leu; mBiP; MIF2; PM23; Polymorphic tumor rejection antigen 1; Putative MAPK-activating protein PM23; RP23-446N16.1; Sez7; SEZ-7; Steroidogenesis-activator polypeptide; TA-3; Targ2; TRA1; Tra-1; Tumor rejection antigen 1; Tumor rejection antigen gp96
Rabbit
IgG
100 μL
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Primary
10945, 3309, 7184
SDS
Documents
Product Certifications
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