KDEL Rabbit anti-Human, Unconjugated, Clone: JB42-04, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Invitrogen MA534715
Positive Control: Rat testis tissue, Mouse testis tissue, 293, HepG2, A549, 293T, rat epididymis tissue, human placenta tissue, human stomach cancer tissue, mouse small intestine tissue.The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins, GRP78 and GRP94 respectively, and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
|Hsp90b1, HSPA5, Kdelr1|
|Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot|
|TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4|
|P11021, P14625, P24390|
|78 kDa glucose-regulated protein; 8030486F04Rik; 94 kDa glucose-regulated protein; AL022860; AU019543; AW215843; baffled; Binding-immunoglobulin protein; BiP; D2Wsu141e; D2Wsu17e; ECGP; Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum resident protein 99; Endoplasmin; ER lumen protein-retaining receptor 1; ERD2; ERD2.1; ERp99; GP96; gp96 homolog; GRP78; GRP-78; Grp94; GRP-94; HDEL; Heat shock protein 70 family protein 5; Heat shock protein 90 kDa beta member 1; Heat shock protein family A member 5; HEL35; HEL-S-125m; HEL-S-89n; Hsce70; HSP70 family protein 5; HSP90B1; HSPA5; I79_019946; I79_020931; Immunoglobulin heavy chain-binding protein; KDEL; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; KDELR1; Lys-Asp-Glu-Leu; mBiP; MIF2; PM23; Polymorphic tumor rejection antigen 1; Putative MAPK-activating protein PM23; RP23-446N16.1; Sez7; SEZ-7; Steroidogenesis-activator polypeptide; TA-3; Targ2; TRA1; Tra-1; Tumor rejection antigen 1; Tumor rejection antigen gp96|
|-20°C, Avoid Freeze/Thaw Cycles, store in dark|
|10945, 3309, 7184|
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