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Tocris™ Ki 16425

LPA1 and LPA3 receptor antagonist

Manufacturer:  Tocris™ 5056/10

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Catalog No. 505610R


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Disclaimers:

For Research Use Only


Specifications

Description

Antagonist of the lysophosphatidic acid receptors LPA1 and LPA3 (Ki values are 0.25 and 0.36µM respectively, in a GTPγS binding assay). Blocks LPA-induced dephosphorylation of Yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (TAZ), inhibiting the Hippo signaling pathway, in HEK293A cells.
  • Chemical Name: 3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid
  • Formula: C23H23ClN2O5S
  • CAS Number: 355025-24-0
  • Solubility: Soluble to 100mM in DMSO and to 20mM in 1eq. NaOH
  • Purity: >98
Description & Specifications

Specifications

Ki 16425
>98
10mg
Ki 16425
474.96
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