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KIAA0141 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 219041AP

Catalog No. 50-173-3632


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Description

Description

DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-Alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-Alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
Specifications

Specifications

KIAA0141
0.36 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q14154, Q9DCV6
KIAA0141
Rabbit
IgG
150 μL
-20°C
Primary
66839, 9812
Western Blot
Unconjugated
KIAA0141
Liquid
Dele1, KIAA0141
KIAA0141 Fusion Protein Ag14615
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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