KIAA1530 Mouse anti-Human, Clone: GT816, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527844
Positive Control: HeLa, A375 Predicted Reactivity: Mouse (83%), Rat (83%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.
|PBS with no preservative|
|UVSS3, UV-stimulated scaffold protein A, KIAA1530|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Recombit protein encompassing a sequence within the N-terminus region of human UVSSA. The exact sequence is proprietary.|
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