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KIP2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549772

Catalog No. PA549772


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Description

Description

The antibody detects endogenous levels of total KIP2 protein.

DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.
Specifications

Specifications

KIP2
Polyclonal
Unconjugated
CIB2
Liquid
CIB2
Synthesized peptide derived from internal of human CIB2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
O75838, Q9Z309
KIP2
Rabbit
IgG
100 μL
-20°C
Primary
10518, 56506
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