KIR2DL3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 189661AP
DescriptionNKAT (NK-associated transcripts) gene products, known as killer immuno-globulin-like receptors or KIRs, downregulate the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells. This family of receptors is characterized by an extracellular region with two to three immunoglobulin-superfamily domains and a cytoplasmic domain with an antigen receptor activation motif (ARAM). KIRs and other inhibitory receptors also possess a common cytoplasmic sequence (I/VxYxxL/V) known as an ITIM (immunoreceptor tyrosine-based inhibitory motif). The human inhibitory human killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3), also referred to as CD158b, is an inhibitory receptor that is specific for the human MHC class I molecule HLA-Cw3 and related alleles.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CD158b, CD158B2, GL183, KIR 023GB, KIR K7b, KIR K7c, KIR2DL3, KIRCL23, MHC class I NK cell receptor, NKAT, NKAT 2, NKAT2, NKAT2A, NKAT2B, p58, p58 NK receptor CL 6|
|KIR2DL3 Fusion Protein Ag5163|
|Antigen Affinity Chromatography|
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