KIR2DS5/CD158g Rabbit anti-Human, Alexa Fluor 647, Clone: 1165A, R&D Systems
Recombinant Monoclonal Antibody
Manufacturer: R&D Systems FAB8920R025
DescriptionKiller-immunoglobulin-like receptors (KIR) are polymorphous activating and inhibitory receptors expressed on the surface of NK cells and some T cells. KIR genes are highly homologous. KIR proteins expressing the long (L) cytoplasmic domain are inhibitory, while KIRs with short (S) cytoplasmic domains are activating. Thus, KIR2DS5 is a 65kDa type I transmembrane activating receptor for NK cells, and is thought to play a role in NK cell function in response to a number of conditions. While many KIR proteins bind HLA-class I molecules, the ligand(s) for KIR2DS5 remain unclear.
|Flow Cytometry 5 uL/10^6 cells|
|killer cell immunoglobulin-like receptor 2DS5, CD158g, killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5, NKAT9|
|Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.|
|Detects human KIR2DS5/CD158g in direct ELISAs.|
|Alexa Fluor 647|
|Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide|
|NS0 mouse myeloma cell line transfected with human KIR2DS5/CD158g His22-His245 Accession # Q14953|
|Protein A or G purified from cell culture supernatant|
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