Invitrogen™ Kir7.1 (KCNJ13) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119868

Catalog No. PIPA5119868

Description

Positive Control: Rat brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, human small intestine tissue. Subcellular Location: Membrane.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

Specifications

• Antigen: Kir7.1 (KCNJ13)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ13
• Gene Alias: Inward rectifier K(+) channel Kir7.1; inward rectifier potassium channel 13; Kcnj13; KIR1.4; KIR7.1; LCA16; Potassium channel, inwardly rectifying subfamily J member 13; potassium channel, inwardly rectifying subfamily J, member 13; potassium inwardly-rectifying channel, subfamily J, member 13; potassium voltage-gated channel subfamily J member 13; SVD
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100040591, 3769, 94341
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O60928, O70617, P86046
• Gene Symbols: KCNJ13
• Immunogen: Recombinant protein within C-terminal human KCNJ13/Kir7.1 from aa 200-aa360.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG