KISS1R Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549719
The antibody detects endogenous level of total KISS1R / GPR54 protein.GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.
|Synthetic peptide corresponding to a region derived from 383-398 amino acids of Human KISS1 receptor|
|Antigen affinity chromatography|
|ELISA, Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|-20° C, Avoid Freeze/Thaw Cycles|
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