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KLC1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Thermo Scientific PA597900

Catalog No. PIPA597900


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Description

Description

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined.
Specifications

Specifications

KLC1
Polyclonal
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q07866
KLC1
Recombit Human Kinesin light chain 1 protein (274-573AA)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
KLC1
Liquid
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3831
Documents
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