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Invitrogen™ KLF4 Monoclonal Antibody (1E6)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA515695
Description
MA5-15695 targets KLF4 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human samples. The MA5-15695 immunogen is purified recombinant fragment of human KLF4 expressed in E. Coli. MA5-15695 detects KLF4 which has a predicted molecular weight of approximately 54kDa.
Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.
Specifications
KLF4 | |
Monoclonal | |
Conc. Not Determined | |
Ascites with 0.03% sodium azide | |
O43474 | |
KLF4 | |
Purified recombinant fragment of human KLF4 expressed in E. Coli. | |
RUO | |
9314 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1E6 | |
Unconjugated | |
KLF4 | |
endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; Ezf; Gklf; gut Kruppel-like factor; gut-enriched krueppel-like factor; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; KLF4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); PNAS-24; PNAS-25; RP11-150J11.1; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; Zie | |
Mouse | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
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