KLHL21 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 169521AP
DescriptionSubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|D4A2K4, Q3U410, Q9UJP4|
|kelch like 21 (Drosophila), Kelch like protein 21, KIAA0469, KLHL21|
|242785, 313743, 9903|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|KLHL21 Fusion Protein Ag10582|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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