KLK3 Mouse anti-Human, Clone: 5A11E2, Abnova™
Mouse monoclonal antibody raised against human KLK3.
Manufacturer: Abnova Corporation MAB12578
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]
|Mouse monoclonal antibody raised against human KLK3.|
|In ascites (0.03% sodium azide).|
|ELISA, Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot|
|ELISA (1:10000) Flow Cytometry (1:200-1:400) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to amino acids 26-251 of human KLK3.|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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