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KPNA7 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA570789
SDSDocumentsProduct Certifications Promotions
This target displays homology in the following species: Cow: 79%; Dog: 93%; Human: 100%; Pig: 79%; Yeast: 90%Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.
|PBS with 2% sucrose and 0.09% sodium azide|
|A9QM74, C1JZ66, C6K7I2|
|synthetic peptide directed towards the C-terminal region of human KPNA7|
|Bovine, Canine, Human, Porcine, Yeast|
|KPNA7, Karyopherin alpha nucleoprotein interactor 7, Importin alpha 8, IPOA8|
|100302505, 402569, 489863, 789280|
|-20° C, Avoid Freeze/Thaw Cycles|
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