KPNA7 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA570789

Catalog No. PIPA570789

Description

This target displays homology in the following species: Cow: 79%; Dog: 93%; Human: 100%; Pig: 79%; Yeast: 90%

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

Specifications

• Antigen: KPNA7
• Classification: Polyclonal
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: A9QM74, C1JZ66, C6K7I2
• Gene Symbols: KPNA7
• Immunogen: synthetic peptide directed towards the C-terminal region of human KPNA7
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Human, Porcine, Yeast
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: KPNA7
• Gene Alias: KPNA7, Karyopherin alpha nucleoprotein interactor 7, Importin alpha 8, IPOA8
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100302505, 402569, 489863, 789280
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid