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KPNA7 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA570789

Catalog No. PIPA570789


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Description

Description

This target displays homology in the following species: Cow: 79%; Dog: 93%; Human: 100%; Pig: 79%; Yeast: 90%

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

KPNA7
Polyclonal
Unconjugated
KPNA7
importin alpha 8; importin subunit alpha-8; IPOA8; karyopherin 7; karyopherin alpha 7 (importin alpha 8); karyopherin subunit alpha 7; Karyopherin subunit alpha-7; KPNA7
Rabbit
Affinity chromatography
RUO
402569
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide
A9QM74
KPNA7
synthetic peptide directed towards the C-terminal region of human KPNA7
100 μL
Primary
Human
Antibody
IgG
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