KRT8 Mouse anti-Human, Clone: UMAB1, liquid, UltraMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene UM500001

Catalog No. 50-168-4839

Description

Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

Specifications

• Antigen: KRT8
• Classification: Monoclonal
• Concentration: 0.5-1.0 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P05787
• Gene Symbols: KRT8
• Immunogen: Human recombit protein fragment corresponding to amino acids 91-381 of human CK8 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: UMAB1
• Conjugate: Unconjugated
• Gene: KRT8
• Gene Alias: CARD2, CK-8, CK8, CYK8, K2C8, K8, KO
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3856
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid