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Thermo Scientific™ Lab Vision™ Ku (p70) Ab-4, Mouse Monoclonal Antibody
Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific™ MS329P
Description
Recommended for multiple molecular biology techniques, Thermo Scientific™ Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results. Mouse Monoclonal Antibody
The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.Host Species: Mouse
Clone: N3H10
Isotype: IgG2b
Species Reactivity: Human, Monkey and Xenopus. Mouse and Hamster (Western Blotting only). Does not react with cow, rabbit and sea urchin.
Epitope: aa 506-541
Immunogen: Human placental extract designated as PSE1-PL
Molecular Weight: 70kDa
Positive Control: BT474, T47D, HEP-G-2 or HeLa cells; Tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunofluorescence
- Immunoprecipitation (Native and denatured)
Note:
USA: RUO; Int'l: RUO
Specifications
| Ku (p70) Ab-4 | |
| Monoclonal | |
| 200μg/mL | |
| Purified Ab with BSA and Azide | |
| Murine | |
| IgG2b | |
| RUO | |
| Primary | |
| Monoclonal |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| N3H10 | |
| Unconjugated | |
| Concentrated | |
| Human placental extract designated as PSE1-PL | |
| 1mL | |
| DNA Repair | |
| Primary | |
| Human, Non-human Primate, Xenopus |
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