Thermo Scientific Lab Vision Ku (p70) Ab-4, Mouse Monoclonal Antibody
Recommended for multiple molecular biology techniques, Thermo Scientific Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results.
Manufacturer: Thermo Scientific MS329PABX
Recommended for multiple molecular biology techniques, Thermo Scientific Ku (p70) Ab-4, Mouse Monoclonal Antibody provides accurate, reproducible results. Mouse Monoclonal AntibodyThe Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Host Species: Mouse
Species Reactivity: Human, Monkey and Xenopus. Mouse and Hamster (Western Blotting only). Does not react with cow, rabbit and sea urchin.
Epitope: aa 506-541
Immunogen: Human placental extract designated as PSE1-PL
Molecular Weight: 70kDa
Positive Control: BT474, T47D, HEP-G-2 or HeLa cells; Tonsil
Cellular Localization: Nuclear
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native and denatured)
USA: RUO; Int'l: RUO
|Ku (p70) Ab-4|
|Ab without BSA/Azide (Frozen)|
|Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Human placental extract designated as PSE1-PL|
|Human, Non-human Primate, Xenopus|
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