Ku70/XRCC6 Mouse anti-Human, Primate, Chicken, Mouse, Rat, Alexa Fluor 350, Clone: KU729, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234663AF350
DescriptionKu70/XRCC6 Monoclonal antibody specifically detects Ku70/XRCC6 in Human,Primate,Chicken,Mouse,Rat samples. It is validated for Immunocytochemistry,Immunofluorescence.
|5′-deoxyribose-5-phosphate lyase Ku70, 5′-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S731, EC 3.6.4.-, EC 4.2.99.-, G22P1Ku70, Ku autoantigen p70 subunit, Ku autoantigen, 70kDa, KU70, ML8,70 kDa subunit, Thyroid-lupus autoantigen, thyroid-lupus autoantigen p70, TLAAD22S671, X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6, X-ray repair cross-complementing protein 6|
|Store at 4°C in the dark.|
|Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|Nuclear extract of human HL-60 cells|
|Chicken, Human, Mouse, Primate, Rat|
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