Invitrogen™ KV1.6 (KCNA6) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115487

Catalog No. PIPA5115487

Description

Antibody detects endogenous levels of total Kv1.6.

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12.

Specifications

• Antigen: KV1.6 (KCNA6)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNA6
• Gene Alias: FLJ25134; HBK2; human brain potassium channel-2; KCNA6; KV1.6; kv2; MK1.6; potassium channel, voltage gated shaker related subfamily A, member 6; potassium channel-Kv2; potassium voltage gated channel, shaker related subfamily, member 6; potassium voltage gated channel, shaker related, subfamily, member 6; potassium voltage-gated channel subfamily A member 6; potassium voltage-gated channel, shaker-related subfamily, member 6; potassium voltage-gated channel, shaker-related, subfamily, member 6; PPP1R96; protein phosphatase 1, regulatory subunit 96; RCK2; voltage-gated potassium channel HBK2; voltage-gated potassium channel protein Kv1.6; voltage-gated potassium channel subunit Kv1.6; voltage-gated potassium channel subunit Kv2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16494, 3742, 64358
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P17658, P17659, Q61923
• Gene Symbols: KCNA6
• Immunogen: A synthesized peptide derived from human KCNA6(Accession P17658), corresponding to amino acid residues R490-V529.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG