Invitrogen™ KV4.3 (KCND3) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA541026

Catalog No. PIPA541026

Description

Peptide sequence: KARLARIRVA KTGSSNAYLH SKRNGLLNEA LELTGTPEEE HMGKTTSLIE Sequence homology: Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%.

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene.

Specifications

• Antigen: KV4.3 (KCND3)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCND3
• Gene Alias: AW045978; BRGDA9; KCND3; KCND3L; KCND3S; Kncd3; KSHIVB; KV4.3; potassium channel alpha subunit Kv4.3 short form; potassium channel Kv4.3; potassium channel Kv4.3L; potassium channel Kv4.3M; potassium channel, voltage gated Shal related subfamily D, member 3; potassium channel, voltage-gated Shal-related subfamily D, member 3; potassium ionic channel Kv4.3; potassium voltage gated channel, Shal-related family, member 3; potassium voltage-gated channel long; potassium voltage-gated channel subfamily D member 3; potassium voltage-gated channel, Shal-related family, member 3; potassium voltage-gated channel, Shal-related subfamily, member 3; SCA19; SCA22; sha1-related potassium channel Kv4.3; voltage-gated K+ channel; voltage-gated potassium channel subunit Kv4.3
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3752, 65195
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q62897, Q9UK17
• Gene Symbols: KCND3
• Immunogen: Synthetic peptide directed towards the middle region of human KCND3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov