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  7. L-368,899 hydrochloride, Tocris Bioscience™

L-368,899 hydrochloride, Tocris Bioscience™

Catalog Number 26411
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
160312-62-9
C26H43ClN4O5S2
591.223
GIUFQWFJHXXXEQ-PHSYAEQHSA-N
2s-2-amino-n-1s,2s,4r-7,7-dimethyl-1-4-2-methylphenyl-1-piperazinyl sulfonyl methyl bicyclo 2.2.1 hept-2-yl-4-methylsulfonyl butanamide
90488775
(2S)-2-amino-N-[(3S)-7,7-dimethyl-4-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-3-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide;hydrochloride
CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)CC34CCC(C3(C)C)CC4NC(=O)C(CCS(=O)(=O)C)N.Cl
This item is not returnable. View return policy
160312-62-9
C26H43ClN4O5S2
591.223
GIUFQWFJHXXXEQ-PHSYAEQHSA-N
2s-2-amino-n-1s,2s,4r-7,7-dimethyl-1-4-2-methylphenyl-1-piperazinyl sulfonyl methyl bicyclo 2.2.1 hept-2-yl-4-methylsulfonyl butanamide
90488775
(2S)-2-amino-N-[(3S)-7,7-dimethyl-4-[[4-(2-methylphenyl)piperazin-1-yl]sulfonylmethyl]-3-bicyclo[2.2.1]heptanyl]-4-methylsulfonylbutanamide;hydrochloride
CC1=CC=CC=C1N2CCN(CC2)S(=O)(=O)CC34CCC(C3(C)C)CC4NC(=O)C(CCS(=O)(=O)C)N.Cl

Description

Potent, non-peptide oxytocin receptor antagonist

Potent, non-peptide and orally active oxytocin receptor antagonist (IC50 = 8.9 nM) that displays > 40-fold selectivity over vasopressin V1a and V2 receptors (IC50 values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractions in vitro and in vivo.
Quantity 1 mg
Formula Weight 591.23
Percent Purity >97%
Chemical Name or Material L-368, 899 hydrochloride

Safety and Handling

Recommended Storage Store at +4°C
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